The Spartanburg Amtrak station is literally a block away from the Marriott.

Amtrak provides direct service to Spartanburg without changeover through the Crescent line, which provides service from New Orleans, LA all the way up to New York City, NY. Other major cities along the way include Philadelphia, Washington DC, Atlanta, Birmingham, Newark, and Charlotte.

If you're willing to make a reasonable changeover of one train, the Carolinian/Piedmont line can also get you direct to Spartanburg, and provides a way to get to SELF from a few other cities including Raliegh, Durham, Richmond, and Baltimore.

Similarly, with one hop the Silver Service/Palmetto line can get you to SELF from Miami, Tampa, Orlando, Jacksonville, and Charleston.

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